Saini, SantoshGoel, NidhiSharma, MadhuArora, BGarg, Nidhi2003-07-182009-05-292003-07-182009-05-292003-07-18Saini S, Goel N, Sharma M, Arora B, Garg N. C-reactive proteins as an indicator of sub-clinical infection in cases of premature rupture of membranes. Indian Journal of Pathology & Microbiology. 2003 Jul; 46(3): 515-6http://imsear.searo.who.int/handle/123456789/73828The present study was conducted on 25 cases of preterm, premature rupture of membranes and 25 patients preterm with intact membranes, between 28-36 weeks of gestation, admitted in the maternity ward of Obstetrics and Gynecology, PGIMS, Rohtak. The sensitivity and specificity of CRP determination was found to be 80% each as an early predictor of subclinical chorioamnionitis. TLC had a low sensitivity of 20% and specificity of 60% in detecting histopathological chorioamnionitis. So CRP estimation is a reliable marker for detection of early choriamnionitis, at the same time, it is quite affordable and reasonably simple.engC-Reactive Protein --analysisChorioamnionitis --bloodFemaleFetal Membranes, Premature Rupture --bloodHumansPredictive Value of TestsPregnancyPregnancy Complications, Infectious --bloodSensitivity and SpecificityJournal Article