Tongia, S KPandya, K1984-04-012009-06-011984-04-012009-06-011984-04-01Tongia SK, Pandya K. Tissue sensitivity to acetylcholine, adrenaline, noradrenaline and serotonin and agents acting on sulphydryl groups. Indian Journal of Physiology and Pharmacology. 1984 Apr-Jun; 28(2): 141-4http://imsear.searo.who.int/handle/123456789/106966Parachloromercury benzoate (PCMB), a sulphydryl inactivator, caused a progressively increasing inhibition of tissue responses to acetylcholine, adrenaline, noradrenaline and serotonin in vitro. This inhibition was progressively and completely reversed by penicillamine, a sulphydryl activator. It is inferred that intact sulphydryl groups are essential for constancy of responses of excitable tissues to the neurotransmitters.engAcetylcholine --pharmacologyAnimalsChloromercuribenzoates --pharmacologyEpinephrine --pharmacologyMuscle Contraction --drug effectsNorepinephrine --pharmacologyPenicillamine --pharmacologyRabbitsRatsSerotonin --pharmacologySulfhydryl Compounds --pharmacologyp-Chloromercuribenzoic AcidIn Vitro