Idhayadhulla, AManilal, AseerMerdekios, BehailuKumar, R Surendra2015-07-072015-07-072015-05Idhayadhulla A, Manilal Aseer, Merdekios Behailu, Kumar R Surendra. Environmental biotoxicity screening of some pyrrole and 1,4-dihydropyridine heterocyclic derivatives. Journal of Applied Pharmaceutical Science. 2015 May; 5(5): 101-105.2231-3354http://imsear.searo.who.int/handle/123456789/159224Synthesis of pyrrole 1-3 and 1,4-dihydropyridine derivatives 4-6 were prepared from condensation method and synthesized compounds were screened for environmental biotoxicity such as Brine shrimp cytotoxicity, Ichthyotoxic, Larvicidal and Nematicidial activities. Among the compounds 3 and 6 shows that highly toxic (LD50: 8.72 and 12.30 μg/mL) against Brain shrimp cytotoxic screening and compound 3 and 6 was highly toxicity ( LD50 : 5.01 and 7.75 μg/mL) against Antifeedant screening (ichthyotoxic profile). The compounds 3 and 6 was highly active (LD50: 12.88 μg/mL, and 14.79 μg/mL) against Larvicidal activity and compound 3 and 6 was highly active (LD50 : 8.20 μg/mL, and 7.43 μg/mL) against Nematicidal activity.enPyrrole derivative14-dihydropyridine derivativeBrine shrimp cytotoxicityIchthyotoxic screeningLarvicidal activityNematicidial activityArticle