Salek, A KKhan, M MAhmed, S MRashid, M IEmran, M AMamun, M A2005-07-022009-05-272005-07-022009-05-272005-07-02Salek AK, Khan MM, Ahmed SM, Rashid MI, Emran MA, Mamun MA. Effect of aerobic exercise on patients with primary fibromyalgia syndrome. Mymensingh Medical Journal. 2005 Jul; 14(2): 141-4http://imsear.searo.who.int/handle/123456789/1111Mymensingh Medical Journal.Sixty eight adult patients of fibromyalgia were included in this prospective study from the Outpatient Department of Physical Medicine and Rehabilitation of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka during the period of January 2003 to June 2003. Study samples were assigned into two treatment groups: Group A (n = 38) with exercise by static bicycle and aerobic walking in addition to tricyclic antidepressant and analgesic and Group B (n = 30) was non exercise group, treated with tricyclic antidepressant and analgesic only. The total duration of treatment was 16 weeks. Pre-treatment (week 0) and post treatment (week 16) evaluation was performed in both groups. Evaluation parameters included pain grade, number of trigger points, occurrence of arousal at night, frequency of micturition and global evaluation by the physician. After 16 weeks, mean improvement of exercise group and non exercise group was 48% and 39% respectively but this difference was not statistically significant. Therefore, from this study it was observed that aerobic exercise showed no significant benefit to fibromyalgia patients.engExerciseFibromyalgia --therapyHumansTreatment FailureClinical Trial