Bredou, Jean BriceAdou, Demel AxelSahi, Zlankeuhon J閞鬽eYebou�, Koffi AppolinaireKabran, Guy Roger MidaBoua, Benson Boua2024-09-242024-09-242024-06Bredou Jean Brice, Adou Demel Axel, Sahi Zlankeuhon J閞鬽e, Yebou� Koffi Appolinaire, Kabran Guy Roger Mida, Boua Benson Boua. Phytochemical Composition, Antibacterial Activities against Multi-Resistant Strains of Pseudomonas aeruginosa and Acinetobacter baumannii of the Bark Extract of Ficus platyphylla Dell. Holl. . International Journal of Medical Research & Health Sciences. 2024-Jun; 33(6): 17-252231-086Xhttps://imsear.searo.who.int/handle/123456789/226848Ficus platyphylla Ficus platyphylla belongs to the Moraceae family which contains nearly 1400 species divided into around forty genera. It is used to manage several diseases in folklore medicine. This study focused on the phytochemical screening and evaluation of the antibacterial potential against Pseudomona aeruginosa and Acinetobacter baumannii of hydroethanolic extract from Ficus platyphylla (FP) bark. Phytochemical and antibacterial activity were carried out according to the literature procedure. Qualitative analyses of FP revealed the presence polyphenols, flavonoids, coumarins, tannins, alkaloids, sterols and terpenes. Quantitative analysis by spectrophotometry showed a phenolic compound content to be 0.878 � 0.02 mg EAG/g DM. The flavonoids content was 0.084 � 0.02 mg EQ/g DM, while flavonic aglycones, anthocyanins and condensed tannins were 0.014 mg EQ/g DM, 0.018 mg EQ/g DM and 0.189 mg EC/g DM, respectively. In vivo antibacterial activity showed that (FP) was ineffective against six (06) multi-resistant strains of Pseudomonas aeruginosa and Acinetobacter baumannii.Ficus platyphyllaphytochemical screeningP. aeruginosaA. baumanniiJournal ArticleIndiaLaboratoire de Chimie Bio-Organique et de Substances Naturelles, Universit� Nangui Abrogoua, 02 BP 801 Abidjan 02, C魌e d扞voireLaboratoire de Chimie Bio-Organique et de Substances Naturelles, Universit� Nangui Abrogoua, 02 BP 801 Abidjan 02, C魌e d扞voire and D閜artement des Sciences et Techniques, Universit� Alassane Ouattara, 01 BP 18 Bouak� 01, C魌e d扞voireLaboratoire de Chimie Bio-Organique et de Substances Naturelles, Universit� Nangui Abrogoua, 02 BP 801 Abidjan 02, C魌e d扞voireLaboratoire de Chimie Bio-Organique et de Substances Naturelles, Universit� Nangui Abrogoua, 02 BP 801 Abidjan 02, C魌e d扞voireLaboratoire de Chimie Bio-Organique et de Substances Naturelles, Universit� Nangui Abrogoua, 02 BP 801 Abidjan 02, C魌e d扞voireLaboratoire de Chimie Bio-Organique et de Substances Naturelles, Universit� Nangui Abrogoua, 02 BP 801 Abidjan 02, C魌e d扞voire