Badem, MerveSener, Sıla OzlemKorkmaz, NuriyeKanbolat, SeydaYildirmiş, SermetOzgen, UfukAliyazicioglu, RezzanKandemir, Ali2020-11-182020-11-182020-06Badem Merve, Sener Sıla Ozlem, Korkmaz Nuriye, Kanbolat Seyda, Yildirmiş Sermet, Ozgen Ufuk, Aliyazicioglu Rezzan, Kandemir Ali. Phenolic Content and Enzyme Inhibition Activities Barbarea auriculata var. paludosa, B. integrifolia and B. plantaginea (Brassicaceae)'s. Journal of Pharmaceutical Research International. 2020 Jun; 32(9): 86-932456-91192231-2919http://imsear.searo.who.int/handle/123456789/215764Barbareagenus has been presented about 12 species, 9 taxon are endemic, in Turkey. In this sudy, enzyme inhibition was carried out on methanolic extract, chloroform extract, ethyl acetate extract, and the remaining aqueous phases from the aerial parts of B. auriculata var paludosa, B. integrifolia, andB. plantagineaspecies and HPLC studies were carried on their methanolic extract in the present study for the first time. Phenolic compounds were determined using reverse phase-high performance liquid chromatography (RP-HPLC). p-OH benzoic acid, vanilic acid, syringaldehyde, coumaric acid, synapic acid and benzoic acid were detected as major phenolic compounds in the species. Assay of enzyme inhibition activitieswere done using spectrophotometric methods. Results of these studies reveal that the extracts from these species have moderate tyrosinase, AChE and BuChE inhibitory activity. In the biological activity studies, it was observed that B. integrifoliawas thehighest activityBarbareabrassicaceaeenzyme ınhibitionphytochemicalPhenolic Content and Enzyme Inhibition Activities Barbarea auriculata var. paludosa, B. integrifolia and B. plantaginea (Brassicaceae)'sJournal ArticleIndiaDepartment of Biochemistry, Faculty of Pharmacy, Karadeniz Technical University, 61080,Trabzon, TurkeyDepartment of Pharmacognosy, Faculty of Pharmacy, Karadeniz Technical University, 61080,Trabzon, TurkeyDepartment of Biochemistry, Faculty of Pharmacy, Karadeniz Technical University, 61080,Trabzon, TurkeyDepartment of Biochemistry, Faculty of Pharmacy, Karadeniz Technical University, 61080,Trabzon, TurkeyDepartment of Biochemistry, Faculty of Pharmacy, Karadeniz Technical University, 61080,Trabzon, TurkeyDepartment of Biology, Faculty of Science, Erzincan University, 24000,Erzincan, Turkey