Khan, VSanghai, AAZala, DBabariya, MJDas, V.2025-05-092025-05-092024-04Khan V, Sanghai AA, Zala D, Babariya MJ, Das V.. A deep dive into chickenpox epidemiology and outbreaks: A retrospective study in a tribal-dominated district of Western India. Indian Journal of Medical Sciences. 2024 Apr; 76(1): 36-421998-36540019-5359https://imsear.searo.who.int/handle/123456789/244947Objectives: This retrospective observational study conducted in the district of Dadra and Nagar Haveli, Western India, over the past 9 years aimed to comprehensively investigate the epidemiology of chickenpox. The objectives were to analyze demographic and clinical characteristics, examine temporal trends, identify outbreak locations, assess outbreak intensity and duration, determine laboratory-confirmed cases, and provide insights for public health interventions. Materials and Methods: The study employed a retrospective approach, gathering data on chickenpox cases in the region. Demographic information, clinical profiles, and outbreak details were analyzed. Temporal variations and seasonal trends were assessed. Laboratory confirmation was achieved through serology and molecular methods. Locations of outbreaks were identified, and their characteristics were evaluated. Results: The study revealed that the 6–10 age groups were most vulnerable, with mild-to-moderate symptoms predominantly observed. Significant variations in cases occurred year round, with peaks between November and February. Out of 25 recorded outbreaks and three early warning signals, Aganwadis, play schools, and schools were common outbreak locations. Most outbreaks were low intensity, and laboratory confirmation identified Clade-1 Varicella-Zoster virus as the causative agent. Conclusion: These findings provide essential insights for public health officials. Identifying the vulnerable age group and high-risk locations allows for targeted vaccination campaigns. Moreover, the study underscores the need for continuous monitoring and surveillance to detect outbreaks early and mitigate their spread effectively, emphasizing the importance of proactive prevention and control measures for chickenpox in the region.VaricellaOutbreakEpidemiologyRisk factorsJournal ArticleIndiaIntegrated Disease Surveillance Program, Directorate of Medical and Health Services, Ahmedabad, IndiaIntegrated Disease Surveillance Program, Directorate of Medical and Health Services, Ahmedabad, IndiaSchool of Applied Sciences and Technology, Gujarat Technological University, Ahmedabad, IndiaDepartment of Microbiology, NAMO Medical Education and Research Institute, Silvassa, IndiaDepartment of Medicine, Directorate of Medical and Health Services, Silvassa, India.