Taksande, Amar MVilhekar, K YJain, MChitre, D2005-09-282009-05-302005-09-282009-05-302005-09-28Taksande AM, Vilhekar KY, Jain M, Chitre D. Pain response of neonates to venipuncture. Indian Journal of Pediatrics. 2005 Sep; 72(9): 751-3http://imsear.searo.who.int/handle/123456789/81661OBJECTIVE: To study the physiological and behavioral response to pain. METHODS: 80 healthy neonates requiring bilirubin estimation, blood sugar etc, were randomly assigned to receive a venous puncture. All parameters were recorded 10 minutes prior, during and 10 minutes after the procedure. Evaluated NIPS score and RR. HR, NIBP and O2 saturation observed on Datex-Ohmeda multimonitor. RESULTS: After the venepuncture, heart rate (p<0.001) and blood pressure (p<0.001) were significantly increased in both the groups but more significant increase was present in Group I (>2.5 kg) as compared to Group II (>2.5 kg). Respiratory rate was also increased but more significant in Group II (p<0.001) whereas oxygen saturation was decreased in both the groups but more significant in Group I (p<0.001). Median Neonatal Infant Pain Scale (NIPS) score was higher in both the Groups (p<0.001). CONCLUSION: The outcome measures appear to be reliable indices of term neonates responses to painful stimulation. NIPS are suitable instruments for neonatal pain evaluation.engBlood PressureFemaleHeart RateHumansInfant BehaviorInfant, NewbornMaleOxygen --bloodPain --diagnosisPain Measurement --methodsPhlebotomy --adverse effectsRespirationJournal Article