Prakash, KiranChandran, Dinu S.Khadgawat2, RajeshJaryal1, Ashok KumarDeepak, Kishore Kumar2016-12-082016-12-082016-01Kiran Prakash1, Dinu S. Chandran1, Rajesh Khadgawat2, Ashok Kumar Jaryal1 and Kishore Kumar Deepak1. Waist Circumference Rather than Body Mass Index is Better Indicator of Insulin Resistance in Type 2 Diabetes Mellitus in North Indian Population. Indian Journal of Physiology and Pharmacology. 2016 Jan-Mar; 60(1): 52-56.http://imsear.searo.who.int/handle/123456789/179527Obesity and insulin resistance (IR) are associated with type 2 diabetes mellitus (DM). Obesity can be quantified by body mass index (BMI) and waist circumference (WC). Similarly, IR is commonly quantified by fasting-plasma-insulin (FPI) and Homeostatic model assessment (HOMA-IR). We aimed our study to find correlation between obesity-parameters and IR especially in the Indian population where despite lower BMI there is more prevalence of type 2 DM. In 34 uncomplicated patients of type 2 DM weight and WC were measured and BMI was calculated. HOMA-IR and FPI level were estimated to assess IR. Significant correlation was found between HOMA-IR and WC (r = +0.368, P = 0.0324) but it was non-significant between HOMAIR and BMI. Correlations were also not significant between FPI and WC or BMI.In conclusion, HOMA-IR and WC are better measures of IR and obesity as compared to FPI and BMI, respectively in type 2 DM.enArticle