Li, XueShen, JieZhao, JinlinTang, ShifangShi, Yuan2016-01-252016-01-252014-11Li Xue, Shen Jie, Zhao Jinlin, Tang Shifang, Shi Yuan. Nasal Intermittent Positive Pressure Ventilation with Heliox in Premature Infants with Respiratory Distress Syndrome: A Randomized Controlled Trial. Indian Pediatrics. 2014 Nov; 51(11): 900-902.http://imsear.searo.who.int/handle/123456789/170902Objective: To assess the efficacy of nasal intermittent positive pressure ventilation with heliox in preterm infants with respiratory distress syndrome. Methods: Premature infants with mild respiratory distress syndrome requiring non-invasive respiratory support were eligible. Infants were randomly assigned to heliox or air-oxygen group. The main outcome was the length of ventilation. Results: Heliox significantly decreased the length of ventilation. The length of ventilation was positively correlated with interleukin-6 at baseline. Carbon dioxide elimination was better in the heliox group. Conclusion: Heliox delivered with nasal intermittent positive pressure ventilation may be effective in reducing length of ventilation and increasing carbon dioxide elimination.enHeliumOxygenPrematurityVentilationArticle