Nair, SPhiske, MSomeshwar, S2023-08-092023-08-092023-03Nair S, Phiske M, Someshwar S. Sole, An Uncommon Location of Borderline Tuberculoid Hansen’s Disease. Indian Journal of Leprosy. 2023 Mar; 95: 73-790254-9395http://imsear.searo.who.int/handle/123456789/222638Leprosy a chronic granulomatous infection, frequently affects areas with relatively low temperature and which are trauma prone. Areas like scalp, palms and soles, groins, genitalia, axillae, eyelids, and perineum, have been described as “immune” to development of leprosy. But clinic-pathological and bacteriological evidence of involvement of these so-called “immune zones” has rarely been documented. Palmoplantar involvement is uncommon in leprosy and could be easily misdiagnosed. We report here a case of 65-year-old male who had a single, well defined, round, 5*5 cm, dull erythematous to hyperpigmented plaque with central clearing over medial aspect of left foot extension as single, erythematous, roundish 2*2cm, plaque with central clearing over medial aspect of left foot just below ankle, for 3 months. There was decreased sensation to hot and cold temperature and to fine touch and pain over the lesions. Sensory examination elsewhere on the body was normal. There was no motor loss, no thickened nerves, no deformities, trophic ulcers or evidence of reaction. Histopathology of sole lesion suggested borderline tuberculoid Hansen’s disease. Stain for AFB was negative. Slit skin smear was negative. Good response to MDT was seen at end of 4 months. Such presentation needs to be kept mind for diagnosis of leprosy for instituting timely and appropriate treatmentHansen’sSolesGranulomaBorderline TuberculoidLeprosyJournal ArticleIndia2nd year ResidentAssociate ProfessorProfessor and Head of Department Dept of Dermatology, MGM Medical College and Hospital, Navi Mumbai-410209, Maharastra, India.