Suvarna, J C2008-07-162009-06-022008-07-162009-06-022008-07-16Suvarna JC. Kayser-Fleischer ring. Journal of Postgraduate Medicine. 2008 Jul-Sep; 54(3): 238-40http://imsear.searo.who.int/handle/123456789/115892Kayser-Fleischer (K-F) ring seen in Wilson's disease (WD) is due to copper deposition in the Descemet's membrane in the sclero-corneal junction. Although believed to be pathognomic of WD, it may be seen in many other hepatic conditions and intraocular copper-containing foreign bodies. The K-F ring detected in pre-symptomatic cases of WD may lead to speedy diagnosis and early management. Co-relation of K-F ring in WD to the disease severity, disappearance with successful treatment, reappearance with non-compliant treatment may aid in optimum management of WD. The importance of K-F ring detection in first-degree relatives of the index case cannot be over-emphasized.engJournal Article