Shukla, Parul JBarreto, Savio GHawaldar, RohiniNadkarni, MandarKanitkar, Gajanan AKerkar, RajendraShrikhande, Shailesh V2009-03-112009-05-292009-03-112009-05-292009-03-11Shukla PJ, Barreto SG, Hawaldar R, Nadkarni M, Kanitkar GA, Kerkar R, Shrikhande SV. Feasibility of laparoscopic abdomino-perineal resection for large-sized anorectal cancers: a single-institution experience of 59 cases. Indian Journal of Medical Sciences. 2009 Mar; 63(3): 109-14http://imsear.searo.who.int/handle/123456789/68678BACKGROUND: Laparoscopic surgery for anorectal carcinoma is steadily gaining acceptance. While feasibility has already been reported, there are no reports addressing the impact of the actual size of large tumors on laparoscopic resectability. AIM: To assess the feasibility and short-term results (including oncological surrogate end points) of performing laparoscopic abdomino-perineal resection (APR) for large rectal cancers. MATERIALS AND METHODS: Data of 59 patients undergoing laparoscopic APR (LAPR) for anorectal malignancies were reviewed retrospectively. Outcomes were evaluated considering the surgical procedure, surface area of the tumor and short-term outcomes. RESULTS: Of the 59 cases, LAPR could be completed in 53 (89.8%) patients. Thirty-one (58.4%) patients had Astler-Coller C2 stage disease. The mean surface area of the tumors was 24+/-17.5 (4-83) cm2. The number of median lymph nodes harvested per case was 12 (1-48). Circumferential resection margin (CRM) was positive in 11 (20.7%) patients. No mortality was reported. CONCLUSION: This appears to be the first report analyzing the impact of the size of the rectal tumor in LAPR. The data clearly indicates that LAPR is not hampered by the size of the tumor. There appears to be a need for preoperative radiotherapy and chemotherapy before undertaking surgery on larger tumors in view of the higher circumferential resection margin positivity.engAdultAgedAged, 80 and overAnus Neoplasms --surgeryFeasibility StudiesFemaleHumansLaparoscopy --methodsMaleMiddle AgedRectal Neoplasms --surgeryJournal Article