Dhar, H LKulkarni, D N1994-10-012009-06-011994-10-012009-06-011994-10-01Dhar HL, Kulkarni DN. Cross reactivity of cephalosporins with penicillin. Indian Journal of Physiology and Pharmacology. 1994 Oct; 38(4): 303-5http://imsear.searo.who.int/handle/123456789/107602Cross antigenicity of cephalosporins with penicillin has been studied experimentally and also by using serum from penicillin sensitive individuals. Definite hypersensitivity reaction was observed in all the animals sensitised with cephalosporins and challenged with penicillin except in rats. Cephalosporins could elicit reaction in tissues sensitised passively with serum obtained from penicillin sensitive individuals.engAnimalsCephalosporins --adverse effectsCross Reactions --immunologyDrug Hypersensitivity --immunologyHypersensitivity, Immediate --immunologyMicePenicillins --adverse effectsRatsJournal Article