Gahlot, Gaurav Pratap SinghMridha, Asit RanjanNath, DevajitKhan, Shah AlamGamanagatti, Shivanand2015-06-292015-06-292015-04Gahlot Gaurav Pratap Singh, Mridha Asit Ranjan, Nath Devajit, Khan Shah Alam, Gamanagatti Shivanand. Intraosseous primary malignant peripheral nerve sheath tumor of the calcaneus: An unusual case and review of literature. Indian Journal of Pathology & Microbiology. 2015 Apr-Jun 58(2): 220-222.http://imsear.searo.who.int/handle/123456789/158603Malignant peripheral nerve sheath tumors (MPNSTs) are uncommon sarcomas that originate from a peripheral nerve or neurofi broma either spontaneously or in association with neurofi bromatosis type 1. MPNSTs account for approximately 5% of all soft tissue malignancies. The tumor is commonly seen in the extremities and trunk. Most of these tumors are high-grade with the potential to recur and metastasize. Common metastatic sites include the lungs, bone, and pleura. Primary intraosseous MPNST is rare, and the diagnosis of intraosseous MPNST, especially in an unusual location is diffi cult because of its cellular origin, histomorphological similarities with other sarcomas, and bone is the most common site for metastasis. We report an unusual case of MPNST of the calcaneus in a young male.enBonecalcaneusmalignant peripheral nerve sheath tumorsS-100Intraosseous primary malignant peripheral nerve sheath tumor of the calcaneus: An unusual case and review of literature.Article