Nadkarni, JayashreeGanesh, HariDwivedi, Rashmi2012-06-112012-06-112011-01Nadkarni Jayashree, Ganesh Hari, Dwivedi Rashmi. Familial clustering of a rare syndrome. Indian Journal of Human Genetics. 2011 Jan; 17(1): 26-28.http://imsear.searo.who.int/handle/123456789/138928Ectrodactyly, ectodermal dysplasia and cleft palate syndrome is a rare autosomal dominant multiple congenital anomaly syndrome with variable expressivity and reduced penetration. The cardinal features are cleft palate/lip, lobster hand deformity, sparse hypopigmented hair, dry scaly skin, and lacrimal and urogenital anomalies. A neonate presented to us with typical features, his mother and other two siblings were also affected.enEECectrodactylyvariable presentationsAbnormalities, Multiple --etiologyAdultChildCleft Lip --epidemiologyCleft Lip --geneticsCleft Palate --epidemiologyCleft Palate --geneticsCluster AnalysisEctodermal Dysplasia --epidemiologyEctodermal Dysplasis --geneticsFoot Deformities, Congenital --epidemiologyFoot Deformities, Congenital --geneticsHand Deformities, Congenital --epidemiologyHand Deformities, Congenital --geneticsFingers --abnormalitiesHair ColorHumansIchthyosis --etiologyInfant, NewbornLacrimal Apparatus --abnormalitiesPigmentation Disorders --etiologySiblingsSyndromeUrogenital Abnormalities --etiologyArticle