Ghosh, K CBiswas, SMisra, A KDhibar, TDas, S K2007-10-052009-05-302007-10-052009-05-302007-10-05Ghosh KC, Biswas S, Misra AK, Dhibar T, Das SK. Limbic encephalitis--an uncommon presentation of systemic malignancy. Journal of the Association of Physicians of India. 2007 Oct; 55(): 731-3http://imsear.searo.who.int/handle/123456789/89453A 46 years, nondiabetic, nonhypertensive woman presented with headache, vomiting, low grade intermittent fever, behavioral abnormality and seizures for last three months. Clinically she had meningism with bilateral papilloedema. Based on CSF analysis, normal CT scan of brain and suspicious lesion in X-ray chest, she was put on anti-tuberculosis therapy. As the patient further deteriorated clinically, MRI of brain was carried out and revealed bilateral increased signal intensities in both medial temporal lobes in T2 and flair sequences. Inj. acyclovir was added considering the diagnosis of herpes simplex encephalitis. In spite of receiving treatment patient gradually became more drowsy and repeat X-ray chest with CT guided FNAC showed picture of adenocarcinoma of lung. So finally, we concluded it to be a case of limbic encephalitis.engAdenocarcinoma --complicationsFatal OutcomeFemaleHumansLimbic Encephalitis --diagnosisLung Neoplasms --complicationsMiddle AgedSeizures --etiologyTemporal Lobe --pathologyCase Reports