Jayaram, NRamaprasad, A VChethan, MSujay, R P1998-07-072009-05-291998-07-072009-05-291998-07-07Jayaram N, Ramaprasad AV, Chethan M, Sujay RP. Tumours and tumour-like conditions of the para-testicular region--a study of morphological features. Indian Journal of Pathology & Microbiology. 1998 Jul; 41(3): 287-95http://imsear.searo.who.int/handle/123456789/74947Twenty two patients with tumours or tumour-like conditions of the para-testicular region (PTR) were diagnosed over a 5 year period. Of these, 16 (73%) were benign with only one true neoplasm (papillary cystadenoma). The tumour-like conditions were comprised of 6 cases of adenomatous hyperplasia of epididymis, 4 cases of spermatic granuloma, 2 cases each of spermatocele and nodular-fibrous proliferation and one mesothelial cyst. Three patients with spermatic granuloma gave a history of trauma. No case of adenomatoid tumour was encountered. Six malignant neoplasms were diagnosed (27%) all of which were sarcomas. Five were primary to the PTR and one was a metastatic deposit from a primary leiomyoblastoma of the mesentery. Among the 5 primary sarcomas were 2 cases each of rhabdomyosarcoma and leiomyosarcoma, and 1 case of liposarcoma. The patient with leiomyoblastoma presented first with a measenteric mass which was followed a month later by a rapidly growing mass in the scrotum. Immunohistochemical staining (IHC) and Electron microscopy (EM) were done in this case. Intra-cytoplasmic myofilaments as well as desmosomes were observed. The patients ranged from 14 to 65 years of age and most presented with painless mass in the scrotum. Follow-up was not possible due to practical difficulties.engAdenoma --pathologyCystadenoma, Papillary --pathologyCysts --pathologyEpididymis --pathologyGranuloma --pathologyHumansHyperplasiaLeiomyoma --pathologyMaleRhabdomyosarcoma --pathologySarcoma --pathologySpermatocele --pathologyTesticular Diseases --pathologyTesticular Neoplasms --pathologyJournal Article