Cabrera, B DValdez, E VGo, T G2009-05-272009-05-271980-12-01Cabrera BD, Valdez EV, Go TG. Clinical trials of broad spectrum anthelmintics against soil-transmitted helminthiasis. The Southeast Asian Journal of Tropical Medicine and Public Health. 1980 Dec; 11(4): 502-6http://imsear.searo.who.int/handle/123456789/35831The Southeast Asian Journal of Tropical Medicine and Public Health.Clinical trials on the three broad spectrum anthelmintics against trichuriasis, ascariasis and hookworm infection were carried out in a rural community in Irosin, Sorsogon. Flubendazole (Fluvermal) appears to be a promising drug against trichuriasis particularly when periodic mass treatment of a community is carried out. Mebendazole (Antiox) also appears to be promising given as single dose during mass treatment of soil-transmitted helminthiasis. As shown in previous studies, oxantel-pyrantel (Quantrel) should be given at 15 mg/kg body weight at 12-hour intervals or 20 mg/kg body weight single dose rather than 10 mg/kg body weight in a single dose when treating trichuriasis.engAnthelmintics --therapeutic useDose-Response Relationship, DrugDrug Combinations --therapeutic useDrug EvaluationFeces --parasitologyHumansMebendazole --analogs & derivativesPhilippinesPyrantel --analogs & derivativesSoilTrichuriasis --drug therapyComparative Study