Pujari, Ravi KumarVidya, N.Motupalli, Naveenkumar2019-12-022019-12-022018-02Pujari Ravi Kumar, Vidya N., Motupalli Naveenkumar. Folic acid and vitamin B12 levels in smokers as compared with healthy Controls. Indian Journal of Mednodent and Allied Sciences. 2018 Feb; 6(1): 26-292347-61922347-6206http://imsear.searo.who.int/handle/123456789/186101Background Smoking is one factor which can alter the folic acid, vitamin B12 and blood cell parameters. The aim of this study was to compare the levels of folic acid, vitamin B12 parameters in smokers as compared with healthy controls. Materials and Methods Totally, 50 patients between the age group 25 and 65 years were recruited for the present study. They were grouped as group I-healthy subjects-and group II-subjects who smoke. Five millilitres of venous blood were collected from all the subjects and submitted for haematological analysis. Results Significant lower levels of folic acid and vitamin B12 levels were noticed in smokers’ subjects. Conclusion The result of the present study signifies that folic acid and vitamin B12 levels are significantly lower in smokers. Smoking has an impact on the folic acid and vitamin B12 levels.SmokingVitamin B12Folic acidPhagocytosisPeriodontitis vitamins defensive mechanismsJournal ArticleIndiaProfessor & Head, S.B. Patil Dental College & Hospital, Bidar, Karnataka, India, raveepujari@yahoo.comAssistant Professor, Department of Periodontics, S.B. Patil Dental College & Hospital, Bidar, Karnataka, India; drvidyanaidu@yahoo.co.inProfessor & Head, Hazaribhag Dental College & Hospital, Hazaribhag, Jharkhand, India, naveen_motupalli@yahoo.com