Larbcharoensub, NoppadolSinghsnaeh, AruneeLeelachaikul, Paisan2009-05-272009-05-272004-09-02Larbcharoensub N, Singhsnaeh A, Leelachaikul P. Primary cardiac angiosarcoma with systemic metastases; a case report and review of the literature. Journal of the Medical Association of Thailand. 2004 Sep; 87(9): 1116-22http://imsear.searo.who.int/handle/123456789/42586Chotmaihet Thangphaet. 26 references.Angiosarcoma is a relatively uncommon primary malignant tumor of the heart derived from the endothelial cells. The authors report a case of primary cardiac angiosarcoma of the right atrium with pulmonary, hepatic, cerebellar and bony metastases in a 46-year-old man who clinically presented as pulmonary hemorrhage. The patient's occupational history had occasional exposure to polyvinyl chloride. The autopsy examination of the cardiac angiosarcoma characterized macroscopically by a right atrial tumor and histologically by anastomosing vascular channels and minute atypical pleomorphic endothelial cells. Immunohistological stainings were positive CD31, CD34 and focal positive factor VII-related antigen. Clinical and pathologic features with briefly reviewed relevant literatures are discussed This is the first reported description in the literature of a primary cardiac angiosarcoma with systemic metastases to multiple organs in Thailand.engDiagnosis, DifferentialFatal OutcomeHeart Neoplasms --pathologyHemangiosarcoma --pathologyHumansMaleMiddle AgedCase Reports