Rathish, BalramGanesh, RameshIsmail, SiyadJeffey, GeorgeToke, Nilesh2020-01-022020-01-022018-05Rathish Balram, Ganesh Ramesh, Ismail Siyad, Jeffey George, Toke Nilesh. Splenic Abscess And Perisplenic Hematoma Complicating Osler. Indian Journal of Case Reports. 2018 May; 4(3): 194-1962454-129X2454-1303http://imsear.searo.who.int/handle/123456789/190553A 52-year-old diabetic gentleman was referred to our center with a 3-week history of fever, left-sided abdominal pain, and progressive breathlessness. He also had history of recurrent epistaxis since childhood. Contrast-enhanced computerized tomography chest and abdomen revealed a splenic abscess, left pulmonary arteriovenous malformation, and left pleural effusion. He was managed conservatively with intravenous antibiotics and an antifungal. A repeat imaging was done after 3 weeks which showed resolution of abscess but an increase in the size of the perisplenic hematoma. An ultrasound guided pigtail catheter was inserted into the peri-splenic hematoma and it was drained. He had also developed an acute cerebellar infarct detected on magnetic resonance imaging of brain, which also showed other chronic infarcts of varying age. A diagnostic nasal endoscopy revealed multiple telangiectasias, and Osler–Weber–Rendu disease (hereditary hemorrhagic telangiectasia [HHT]) was diagnosed according to Curacao criteria. Symptomatic splenic involvement may be a rare manifestation of HHTJournal ArticleIndiaPG-Registrar CMT, Department of Internal Medicine, Department of Medical Gastroenterology, Aster Medcity, Kochi, IndiaLead Consultant, Department of Medical Gastroenterology, Aster Medcity, Kochi, IndiaSenior Consultant, Department of Medical Gastroenterology, Aster Medcity, Kochi, IndiaConsultant, Department of Medical Gastroenterology, Aster Medcity, Kochi, IndiaSenior Speacialist, Department of Medical Gastroenterology, Aster Medcity, Kochi, India