Krishna, M. SaiPradeepa, L. UmaAmbati, SwethaRavintula, Sriram2020-09-242020-09-242019-09Krishna M. Sai, Pradeepa L. Uma, Ambati Swetha, Ravintula Sriram. Study on Clinical and Laboratory Profile of Patients with Primary Hyperthyroidism. International Journal of Contemporary Medical Research . 2019 Sep; 6(9): i1-i62393-915X2454-7379http://imsear.searo.who.int/handle/123456789/202595Introduction: Thyroid hormones regulate numerousmetabolic processes. Therefore, any alteration in theirsynthesis or function has important health implications. Aims:Study done on clinical and laboratory profile of patients withprimary hyperthyroidism.Material and methods: Descriptive and cross-sectionalStudy done amongst the in-patients with a proven PrimaryHyperthyroidism. 60 Patients with newly diagnosed PrimaryHyperthyroidism above the age of 18 years. Diagnostichormone levels i.e. increased SERUM T3,T4 levels withdecreased TSH levels.Results: out of 60 patients of Hyperthyroidism, 60% wereGrave’s disease, 28.3% were Toxic multinodular goiter and1.7% was toxic solitary nodule. Majority of TSH values wereless than 0.01. In all most all cases both T3 and T4 wereelevated (predominantly T4). There was no difference inT3, T4 and TSH values among the three common causes ofHyperthyroidism. Wayne’s clinical Diagnostic index had goodcorrelation with T3 (p value of 0.024), T4 and TSH. When theWayne’s index was high, T3 & T4 were also high and TSHwas low.Conclusion: Wayne’s clinical index correlate quite well withthe thyroid function tests particularly raised T3 and the scorecould be a useful tool for follow up of hyperthyroid patientsClinical and Laboratory ProfilePrimary HyperthyroidismJournal ArticleIndiaAssistant Professor, Department of General Medicine: Chalmeda Anand Rao Institute of Medical Sciences, KarimnagarFellow in pain, Department of Anaesthesia and Pain, Yashoda Hospital, Secunderabad, TelanganaMICU Specialist, Department of Anaesthesia, Niloufer Hospital, Hyderabad, TelanganaJunior Consultant, Department of Anaesthesia, KIMS Hospital, Secunderabad, Telangana, India.