Maheshwari, J RDesai, S VHansotia, M DWalvekar, V R1989-04-012009-06-021989-04-012009-06-021989-04-01Maheshwari JR, Desai SV, Hansotia MD, Walvekar VR. Anti-convulsant therapy in eclampsia. Journal of Postgraduate Medicine. 1989 Apr; 35(2): 66-9http://imsear.searo.who.int/handle/123456789/115499Seventy four patients presented with eclampsia at N.W.M. Hospital. Bombay. Among the patients with eclampsia, 64.9% were primis, 29.7% were gravida II-IV and 5.4% were grand multis. As many as 40.5% patients were less than 20 years of age, while 2.7% were over 30 years of age. 48.7% had antepartum convulsions, 40.5% had intrapartum convulsions, while 8 patients convulsed in the postpartum period. Besides standard management of eclamptic patients, 3 protocols of anticonvulsant therapy were utilised. 27% were managed with diphenyl hydantoin sodium, 43% with magnesium sulphate, and 30% by combination of diazepam and pentazocine. The maternal and perinatal outcome was evaluated. Control of convulsions was superior with magnesium sulphate while perinatal outcome was best with diphenyl hydantoin.engAdultAnticonvulsants --therapeutic useDiazepam --therapeutic useDrug Therapy, CombinationEclampsia --drug therapyFemaleHumansInfant MortalityMagnesium Sulfate --therapeutic useMaternal MortalityPentazocine --therapeutic usePhenytoin --therapeutic usePregnancyComparative Study