Raveendran-Nair, AKGeorge, NAKumar, RSreekumar, AJayasree, K2020-04-102020-04-102018-06Raveendran-Nair AK, George NA, Kumar R, Sreekumar A, Jayasree K. Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid gland: Not so indolent a neoplasm?. Indian Journal of Pathology and Microbiology. 2018 Jun; 61(2): 242-2440377-49290974-5130http://imsear.searo.who.int/handle/123456789/196177A 58-year-old female, a known diabetic and hypertensive, presented with left-sided swelling on the anterior aspect of the neck of 1-year duration, which was rapidly increasing in size for the past 6 months. She was on Eltroxin for hypothyroidism for the past 1 year. Computed tomography study of the neck showed a nodule in the left lobe of thyroid which on fine-needle aspiration was suspicious for malignancy. Total thyroidectomy with left posterolateral lymph node dissection was done. Histopathological examination showed sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) of the thyroid gland with lymph node metastasis. SMECE of the thyroid was initially thought to be a low-grade malignancy with indolent clinical behavior. However, our case showed extra thyroidal spread with lymph node metastasis, necessitating adjuvant therapy for our patient. Such aggressive behavior has been noted in few earlier case reports also.Sclerosing mucoepidermoid carcinoma with eosinophiliathyroidindolentJournal ArticleIndiaDepartment of Pathology, Regional Cancer Centre, Thiruvananthapuram, Kerala, IndiaDepartment of Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, IndiaDepartment of Radiotherapy, Regional Cancer Centre, Thiruvananthapuram, Kerala, IndiaDepartment of Nuclear Medicine, Regional Cancer Centre, Thiruvananthapuram, Kerala, India