Emmanuel, Uzodinma IwuozoReginald, Onyeadumarakwe ObiakoTerhemen, Joseph IgbuduAdesola, Ogunniyi2020-10-162020-10-162020-05Emmanuel Uzodinma Iwuozo, Reginald Onyeadumarakwe Obiako, Terhemen Joseph Igbudu, Adesola Ogunniyi. Relationship between Demographic, Clinical, Psychosocial Factors and Health-related Quality of Life among Persons with Epilepsy in Zaria Northern Nigeria. Journal of Advances in Medicine and Medical Research. 2020 May; 32(7): 73-822456-8899http://imsear.searo.who.int/handle/123456789/210383Introduction:Thereisagrowingglobalinterestontheeffectofepilepsyonthesubjectivehealth-relatedqualityoflife(HRQoL)ofthesufferers.Severaldemographic,clinical,andpsychosocialfactorshavebeenattributedascontributorytothepoorHRQoLinpatients(persons)withepilepsy(PWE).Aim:Thisstudyevaluatedtherelationshipbetweendemographic,clinicalandpsychosocialcharacteristicsofPWEandtheirHRQoL StudyDesign:Across-sectionalstudy.PlaceandDurationofStudy:StudycarriedoutatNeurologyclinicofAhmaduBelloUniversityTeachingHospitalKadunaState,NigeriafromSeptember2013toDecember2014.Methodology:ConsecutivelypresentingPWEonfollow-upforatleast1year,18yearsandabovewererecruitedafterobtainingethicalapprovalandinformedconsent.StructuredquestionnaireandtheWorldHealthOrganizationQualityof Life(WHOQOL-Bref)instrumentwereutilizedforthestudy.ThedatawasanalyzedusingSPSSversion17withp-valuesetatlessthan0.05.Results:Theparticipantswereonehundredwithmedianageof29years.ThefactorsfoundtohavesignificantrelationshipwithHRQoLweredemographicvariableslikemaritalstatus(F=3.250,p=0.025)andmonthlyincome(t=-2.883;p=0.005);psychosocialfactorslikepresenceofperceivedstigmaordiscrimination(χ2=2.427,p=0.017),presenceofdepressivesymptomintheprecedingmonth(χ2=3.164,p=0.002)andavailabilityofsocialsupport(χ2=3.328,P=0.001).TherewasnosignificantrelationshipfoundbetweenclinicalfactorsandHRQoLofPWE(p>0.05).Conclusion:Thedemographicfactors(maritalstatusandmonthlyincome)andpsychosocialfactors(stigma,depressionandsocialsupport)hadasignificantrelationshipwithHRQoLinPWE.Thereisaneedtoofferevidence-basedandfocusedcaretothesufferersofthisillnessRelationshipdemographicclinicalpsychosocialhealth related quality of lifepersons with epilepsyJournal ArticleIndiaNeurology Unit, Department of Medicine, Benue State University Teaching Hospital, Makurdi, Benue State, NigeriaNeurology Unit, Department of Medicine, Ahmadu Bello University Teaching Hospital, Shika-Zaria, Kaduna State, NigeriaDepartment of Family Medicine, Benue State University Teaching Hospital, Makurdi, Benue State, NigeriaNeurology Unit, Department of Medicine, University College Hospital, Ibadan, Oyo State, Nigeria