Boonyaleepun, SBoonyaleepun, CSchlactus, J L2009-05-272009-05-271999-03-14Boonyaleepun S, Boonyaleepun C, Schlactus JL. Effect of IVIG on the hair regrowth in a common variable immune deficiency patient with alopecia universalis. Asian Pacific Journal of Allergy and Immunology. 1999 Mar; 17(1): 59-62http://imsear.searo.who.int/handle/123456789/36981Published by the Allergy and Immunology Society of Thailand.Common variable immune deficiency (CVID) is associated with a variety of autoimmune diseases. Alopecia universalis (AU), believed to have an autoimmune basis, has been found in 1.6% of patients with CVID. Intravenous immunoglobulin (IVIG) therapy is used in various immunodeficiency disorders including CVID, and benefit has been shown in the therapy of autoimmune diseases. We report a patient with CVID and AU treated with IVIG who experienced significant hair regrowth. An 8-year-old girl with CVID and AU was treated with IVIG 400 mg/kg every 4 weeks. Since her second dose of IVIG, regrowth of eyelashes, eyebrows, body and scalp hair was observed in this patient. At present, about 1 year treat-meant of IVIG, significant hair regrowth is noted with 5-6 cm of scalp hair. We believe that IVIG may be beneficial in the treatment of AU, at least in patients with CVID.engAlopecia --complicationsChildCommon Variable Immunodeficiency --complicationsFemaleHair --drug effectsHumansImmunoglobulins, Intravenous --therapeutic useTreatment OutcomeCase Reports