Malarvizhi, DMathur, P P2009-05-282009-05-281996-06-01Malarvizhi D, Mathur PP. Renal beta-glucuronidase activity is a bioassay of serum testosterone levels in rats. Indian Journal of Experimental Biology. 1996 Jun; 34(6): 582-3http://imsear.searo.who.int/handle/123456789/61947Alteration in the testosterone levels in experimental animals is reflected by a corresponding change in kidney beta-glucuronidase activity. With a view to use change in renal beta-glucuronidase activity as a bioassay of androgens, the activity of renal beta-glucuronidase and serum testosterone levels were determined following treatment with cisplatin for 3 alternate days. Levels of both renal beta-glucuronidase activity and serum testosterone were significantly decreased in cisplatin-treated rats. It is therefore suggested that kidney beta-glucuronidase activity can be used as a bioassay of androgens.engAnimalsBiological AssayGlucuronidase --analysisKidney --enzymologyMaleRatsRats, WistarTestosterone --bloodJournal Article