Das, Satya RanjanPattanaik, Manu2020-01-022020-01-022018-07Das Satya Ranjan, Pattanaik Manu. Comparison between the Intracervical Route (Solution form) and Intravaginal Route (Tablet Form) Misoprostol Administration for Cervical Priming in Early Pregnancy Failure. Annals of International medical and Dental Research. 2018 Jul; 4(4): 13-152395-28222395-2814http://imsear.searo.who.int/handle/123456789/192695Background:Misoprostol has been used for cervical priming before suction evacuation in early pregnancy failure. The procedure widely accepted and practised. we evaluate the efficacy of misoprostol in intracevical solution form v/s vaginal tablet form for cervical priming before suction evacuation. Methods: A prospective clinical trial was carried out in 200women presenting with early pregnancy failure between period of gestation (6-12 wks) who were sequencially allocated to two groups of 100 each. Both group received 200ug misoprostol 1 hr prior to suction evacuation by either solution or tablet form. Results: Demographically both groups are similar for all period of gestation. misoprostol solution significantly improve cervical dilatation (p<0.001) with reduced suction evacuation period compare with tablet form. No major complication occurs in ether groups. Conclusion: The solution form is an effective alternative to tablet form of misoprostol of cervical priming. To the best of our knowledge this may be the first study to compare the efficacy of misoprostol in intracervical solution form vs intravaginal tablet form for cervical priming before suction evacuationJournal ArticleIndiaAssistant Professor, Department of Obstetrics and Gynaecology, Hi-Tech Medical College & Hospital, Rourkela, Odisha, India.Director, Senior Obstetrics and Gynaecology Specialist, Shanti Memorial Hospital and IVF Centre, Rourkela, Odisha, India