Vinekar, AnandWu, Wei-ChiLorenz, BirgitBavaskar, SnehalBerrocal, AudinaLopez-Cañizares, AshleyFung, NicholasLam, Wai ChingM.llop, StephanieMangalesh, ShwethaOzdek, SengulToth, Cynthia2025-06-192025-06-192025-05Vinekar Anand, Wu Wei-Chi, Lorenz Birgit, Bavaskar Snehal, Berrocal Audina, Lopez-Cañizares Ashley, Fung Nicholas, Lam Wai Ching, M.llop Stephanie, Mangalesh Shwetha, Ozdek Sengul, Toth Cynthia. Rare pediatric retinal diseases: A review. Indian Journal of Ophthalmology. 2025 May; 73(5): 622-6360301-47381998-3689https://imsear.searo.who.int/handle/123456789/249887Rare pediatric retinal disorders present significant challenges in diagnosis and management due to their limited prevalence and diverse clinical manifestations. This paper provides a comprehensive review of select rare retinal disorders affecting the pediatric population, focussing a brief on their epidemiology, clinical characteristics, diagnostic modalities, and therapeutic interventions. Through a systematic examination of current literature and clinical case studies, this review aims to elucidate the distinct features and challenges associated with each disorder. Despite the rarity of these conditions, their impact on visual function and quality of life necessitates heightened awareness among clinicians and researchers to facilitate timely diagnosis, appropriate management, and improved outcomes for affected children as their visual systems are still developing. Furthermore, advancements in diagnostic modalities such as fundus fluorescein angiography, optical coherence tomography, electroretinography, and genetic testing are examined for their role in enhancing our understanding of rare pediatric retinal disorders and facilitating early intervention strategies. The literature selection for this article was conducted through PubMed, Google Scholar, and the Cochrane Library databases. A thorough systematic search was carried out for the concerned diseases. Relevant review articles, original research studies, case series, and reports were examined. Additionally, references from these sources were reviewed and included if they provided pertinent information on the topic. The search was not restricted by publication date.Coats diseasefamilial exudative vitreoretinopathyincontinentia pigmentiinherited diseasespediatric uveitispersistent fetal vasculaturepediatric retinal diseasesretinoschisisshaken baby syndromesticklerstumorsJournal ArticleIndiaDepartment of Pediatric Retina, Narayana Nethralaya Eye Institute, Bengaluru, Karnataka, IndiaDepartment of Ophthalmology, Linkou Chang Gung Memorial Hospital, and College of Medicine, Chang Gung University, Taoyuan, TaiwanDepartment of Ophthalmology, University Hospital Bonn, GermanyMedical and Paediatric Retina, Narayana Nethralaya, Karnataka, IndiaRetina, Bascom Palmer Eye Institute, Florida, United StatesDepartment of Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida, USA, United StatesDepartment of Ophthalmology, Vancouver Acute, University of British Columbia, CanadaDepartment of Ophthalmology, Vancouver Acute, University of British Columbia, CanadaDepartment of Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida, USA, United StatesDepartment of Ophthalmology, Duke Eye Institute, Durham, North Carolina, USA, United StatesDepartment of Ophthalmology, Gazi University, School of Medicine, Ankara, TurkeyDepartment of Ophthalmology, Duke Eye Institute, Durham, North Carolina, USA, United States