Gupta, S KSharma, UGupta, M LSharma, D K1989-02-012009-05-271989-02-012009-05-271989-02-01Gupta SK, Sharma U, Gupta ML, Sharma DK. Acridine orange stain--a rapid method for diagnosis of neonatal septicemia. Indian Pediatrics. 1989 Feb; 26(2): 153-5http://imsear.searo.who.int/handle/123456789/12860The present study included 150 newborns; 100 clinically septic and 50 clinically aseptic who served as control. Out of 100 clinically septic newborns, blood culture was positive in 33 (33%), serum CRP was positive in 64 (64%) and acridine orange stained buffy coat smear was positive in 76 (76%). Serum CRP was found to be the most specific (specificity 96%) and acridine orange stained buffy coat smear examination the most sensitive (sensitivity 94.3%) test for diagnosis of neonatal septicemia.engAcridine Orange --diagnostic useC-Reactive Protein --analysisHumansInfant, NewbornSepsis --diagnosisAcridine orange stain--a rapid method for diagnosis of neonatal septicemia.Comparative Study