Sahare, HBarapatre, AShah, MPVengurlekar, SGKinage, KGPathare, SS.2024-12-022024-12-022024-02Sahare H, Barapatre A, Shah MP, Vengurlekar SG, Kinage KG, Pathare SS.. Exploring Lipid Abnormalities in Senile Cataract: A Cross-Sectional Investigation. Ophthalmology Research: An International Journal. 2024 Feb; 19(1): 31-352321–7227https://imsear.searo.who.int/handle/123456789/240612Background: Age-related cataracts (ARC) are a common cause of vision impairment in older adults. Previous studies have suggested that abnormal Lipid profile and oxidative stress may contribute to the development and progression of ARC. Aim: The aim of this study was to compare the serum Lipid profile levels in patients with ARC and healthy controls. Materials and Methods: This was a case-control study involving 50 patients with ARC and 50 age and gender-matched controls. Serum Lipid profile levels were measured using standard methods. The data were analyzed using t-test. A P-value of less than 0.05 was considered statistically significant. Results: The results showed that the mean serum level of HDL Cholesterol was significantly lower in the ARC group than in the control group, while the mean serum level of triglyceride was significantly higher in the ARC group than in the control group. Conclusion: This study indicates that altered lipid profile may be a risk factor for ARC.Age-related cataractserum lipidcase-control studylow-density lipoprotein cholesterolJournal ArticleIndiaDepartment of Ophthalmology, T.N.M.C and B.Y.L. Nair Hospital, Mumbai, IndiaDepartment of Biochemistry, T.N.M.C and B.Y.L. Nair Hospital, Mumbai, IndiaLaboratory Technician, Bai Gulbai Municipal Dispensary G North, Mumbai, IndiaLaboratory Technician,45 BDD Municipal Dispensary G South, Mumbai, IndiaLaboratory Technician, Drug Deaddiction Centre, Psychiatry Department, Seth GSMC and KEMH Parel Mumbai, IndiaDepartment of Physiology, Laboratory Technician, Seth GSMC and KEMH Parel Mumbai, India.