Dash, R JKhandekar, SKak, V K1990-06-012009-05-301990-06-012009-05-301990-06-01Dash RJ, Khandekar S, Kak VK. Persistent Cushing's disease in a patient with invasive pituitary adenoma. Journal of the Association of Physicians of India. 1990 Jun; 38(6): 428-30http://imsear.searo.who.int/handle/123456789/85532A patient with invasive basophilic pituitary adenoma is described, in whom the hypercortisolaemia and clinical features persisted despite two attempts to reduce the tumour mass by transfrontal pituitary surgery and external beam radiotherapy. The patient responded to oral ketoconazole with clinical and biochemical improvement.engAdenocarcinoma --bloodAdultCombined Modality TherapyCushing Syndrome --bloodFemaleHumansHydrocortisone --bloodKetoconazole --therapeutic usePituitary Neoplasms --bloodCase Reports