Kumar, M Krishna2016-03-042016-03-042015-10Kumar M Krishna. Adult Onset Leuko-encephalopathy, Cerebral Calcifications and Cysts. Annals of International Medical and Dental Research. 2015 Oct-Dec; 1(3): 353-357.http://imsear.searo.who.int/handle/123456789/175176Leuko-encephalopathy, brain calcifications and cysts (LCC) known as Labrune syndrome, is a rare syndrome. It is primarily described in childhood and adolescence as presenting with neurological impairment of relatively rapid progression and intra-cerebral hemorrhage that frequently leads to death. The etiology is unknown & there is no specific clinical feature suggestive of this disorder. Here in, we report a 34-year old man with LCC who had chronic Headache & neurological symptoms beginning in adulthood and discuss recently described entities in view of the relevant literature.enBrain Calcifications & CystsLabrune SyndromeLeukoencephalopathyArticle