Dewan, AChattopadhyay, PKulkarni, P K2009-05-282009-05-281995-03-01Dewan A, Chattopadhyay P, Kulkarni PK. N-acetyltransferase activity--a susceptibility factor in human bladder carcinogenesis. Indian Journal of Cancer. 1995 Mar; 32(1): 15-9http://imsear.searo.who.int/handle/123456789/50097A higher proportion of slow acetylator phenotypes has previously been found among bladder cancer patients. In the present study carried out among 77 male bladder cancer patients and 80 non-cancer controls, 59.74% of the patients and 35% of the controls were slow acetylator phenotypes (p < 0.01). The odds of developing bladder cancer was also observed to be significantly higher among smokers than non-smokers (p < 0.01). The findings suggest that slow N-acetyl phenotype is a susceptibility factor in bladder carcinogenesis.engAdultAge FactorsAgedAged, 80 and overArylamine N-Acetyltransferase --geneticsDisease SusceptibilityHumansMaleMiddle AgedPhenotypeReference ValuesSmoking --metabolismUrinary Bladder Neoplasms --enzymologyJournal Article