K SongraksaS Lerkiatbundit2011-02-222011-02-222009-12-222009-12-22Songklanagarind Medical Journal; Vol. 27 No. 1 Jan-Feb 2009; 35-49http://imsear.searo.who.int/handle/123456789/131936Objective: To test the validity and reliability of the Thai version of the Diabetes-39 (D-39) instrument.Design: Correlational study. Materials and methods: Translation of the English questionnaire into Thai employed the translation-back translation technique. Preliminary testing included assessment by 3 experts, think-aloud testing in 5 patients and pretesting in 30 patients. A large-sample study was conducted in 397 diabetic patients at 6 community hospitals in southern Thailand. The majority of subjects (93.2%) completed the scale through an interview.Results: Exploratory factor analytic results revealed a six-factor structure underlying the D39. The newly identified factor was other health problems and diabetic complications, comprising of 3 items. Thirty-one items from the 36 remaining items clustered into 5 factors identified by the previous studies. The size of nearly all factor loadings were about 0.40 or greater than 0.40. All six dimensions of the D-39 showed reliability indices greater than 0.70. The patterns of the relationship between the D-39 and the SF-36 or self-perception of disease severity were consistent with those hypothesized. All dimensions of the D-39 could reliably discriminate among subjects with/without comorbidities or those with/without insulin injection or those with/without complications. However, the effect size was rather small, less than 0.50.Conclusions: The D-39 Thai version shows an acceptable level of reliability and validity. The study suggests 6 factors underlying the D-39. However, further studies in a different sample are needed to confirm theresult on factor structure.en-USFaculty of Medicine, Prince of Songkla University, Songkla, ThailandDevelopment of a disease specific quality of life instrument: Thai version of the Diabetic-39Original Article