Bani, SSingh, SSingh, G BSingh, O V2009-05-282009-05-281995-11-01Bani S, Singh S, Singh GB, Singh OV. 2-(2,3-dimethylchromon-6-yl) propanoic acid (OVS-103): a potent anti-inflammatory agent. Indian Journal of Experimental Biology. 1995 Nov; 33(11): 841-4http://imsear.searo.who.int/handle/123456789/56561The compound OVS-103 showed dose-dependent anti-inflammatory and anti-arthritic effects in different acute and chronic test models in rats and mice. It produced inhibition of the exudate volume and the migration of leucocytes in the carrageenan induced pleurisy test in rats. OVS-103 showed poor inhibitory effect on granuloma formation induced by cotton pellet and had no anti-pyretic and analgesic property. ALD50 in both rats and mice was more than 2000 mg/kg, p.o. and 1500 mg/kg, i.p.engAnimalsAnti-Inflammatory Agents, Non-Steroidal --pharmacologyArthritis --drug therapyCapillary Permeability --drug effectsChromones --pharmacologyDisease Models, AnimalEdema --drug therapyFemaleLethal Dose 50MicePleurisy --drug therapyPregnancyRatsUterus --drug effectsJournal Article