Singal, AnjaliTirkey, NaveenMuragundla, AnjaneyuluChopra, Kanwaljit2009-05-282009-05-282006-11-09Singal A, Tirkey N, Muragundla A, Chopra K. Green tea [Camellia sinensis (L.) O. Kuntze] extract reverses the despair behaviour in reserpinised and diabetic mice. Indian Journal of Experimental Biology. 2006 Nov; 44(11): 913-7http://imsear.searo.who.int/handle/123456789/61816Green tea (C. sinensis) extract (GTE) dose dependently produced reversal of despair in normal, reserpinised and diabetic mice, thereby demonstrating an antidepressant effect. Although the exact mechanism is yet to be explored, the possible inhibition of catechol-o-methyl transferase and monoamine oxidase enzymes may be responsible for antidepressant activity of GTE.engAnimalsAntidepressive Agents --pharmacologyBehavior, Animal --drug effectsCamellia sinensis --chemistryDiabetes Mellitus, Experimental --bloodHabituation, Psychophysiologic --drug effectsHelplessness, LearnedMaleMiceMice, Inbred StrainsPhytotherapy --methodsPlant Extracts --pharmacologyReserpine --pharmacologyStreptozocinSwimmingGreen tea [Camellia sinensis (L.) O. Kuntze] extract reverses the despair behaviour in reserpinised and diabetic mice.Comparative Study