Yien, BandanaGhosh, ArnavPriyadarshini, Smruti RSahu, Srikant KPadhy, DebanandaAli, Mohammad HasnatDas, Sujata2023-08-252023-08-252022-02Yien Bandana, Ghosh Arnav, Priyadarshini Smruti R, Sahu Srikant K, Padhy Debananda, Ali Mohammad Hasnat, Das Sujata. Early changes in host and donor lenticule thickness after Descemet stripping endothelial keratoplasty. Indian Journal of Ophthalmology. 2022 Feb; 70(2): 529-5341998-36890301-4738http://imsear.searo.who.int/handle/123456789/224135Purpose: To analyze the early changes in host and donor lenticule thickness after Descemet Stripping Endothelial Keratoplasty (DSEK). Methods: DSEK was performed on 32 eyes of 31 patients. Pre? and post? operative slit lamp examination and anterior segment Optical Coherence Tomography (OCT) was done on day?1, day?7, 1 month, and 3 months. Results: There were significant changes in host, lenticule, and total corneal thicknesses between day?1 and day?7, and day?7 and 1 month. There were significant changes in host thickness and total corneal thickness between 1 month and 3 months. Thickness changes were significant between day?1 and day?7, and 1 month and 3 months for thick and thin host, respectively, whereas these changes were observed both for thick and thin host between day?7 and 1 month. Similarly, significant changes were observed between day?7 and 1 month, and day?7 and 1 month in thin lenticule whereas in case of thick lenticule, it was observed till the 3 months follow?up period. There was a significant improvement in visual acuity till the 3 months follow?up period. No significant correlation was observed between visual acuity and host and lenticule thickness. Conclusion: The thicknesses of host and lenticule decrease continuously. Lenticule thickness stabilizes before host. Thinner cornea stabilizes earlier compared to thicker corneaDSEKlenticulelenticule thicknessEarly changes in host and donor lenticule thickness after Descemet stripping endothelial keratoplastyJournal ArticleIndiaCornea and Anterior Segment Service, L V Prasad Eye Institute, Bhubaneswar, Odisha, IndiaDepartment of Biostatistics, L V Prasad Eye Institute, Hyderabad, Telangana, India