Dutta, A SChaudhuri, A K2009-05-282009-05-281991-10-01Dutta AS, Chaudhuri AK. Neuropharmacological studies on the venom of Vipera russelli. Indian Journal of Experimental Biology. 1991 Oct; 29(10): 937-42http://imsear.searo.who.int/handle/123456789/55889Neuropharmacological studies have been conducted on the venom of V. russelli on experimental animals. The venom was found to produce alteration in general behaviour pattern, reduction in spontaneous motility, hypothermia, potentiation of pentobarbitone hypnosis, analgesia, reduction in exploratory behaviour pattern, muscle relaxant action, and suppression of aggressive behaviour. The venom caused a significant increase in brain GABA content in mice. The observations are suggestive of a potent CNS-depressant action of V. russelli venom.engAggression --drug effectsAnimalsBehavior, Animal --drug effectsBody Temperature --drug effectsBrain --metabolismChlorpromazine --pharmacologyDose-Response Relationship, DrugMiceMuscle Relaxation --drug effectsNervous System --drug effectsPain --drug therapyRatsSeizures --drug therapySleep --drug effectsViper Venoms --pharmacologygamma-Aminobutyric Acid --biosynthesisJournal Article