Trivedi, P JPatel, P SBrahmbhatt, M MPatel, B PGajjar, S BDalal, E NShukla, S NShah, P MBakshi, S R2012-06-082012-06-082009-09Trivedi P J, Patel P S, Brahmbhatt M M, Patel B P, Gajjar S B, Dalal E N, Shukla S N, Shah P M, Bakshi S R. A new recurring chromosome 13 abnormality in two older patients with de novo acute myeloid leukemia: An Indian experience. Indian Journal of Human Genetics. 2009 Sept; 15(3): 137-139.http://imsear.searo.who.int/handle/123456789/138886We report here two cases of trisomy 13 in acute myeloid leukemia M1 subtype. short-term unstimulated bone marrow and peripheral blood lymphocyte culture showed 47, XY, +13 in all metaphase plates and trisomy 13 was confirmed with whole chromosome paint probes. Trisomy 13 in AML-M1 is a rare numerical abnormality. This is the first Indian report of sole trisomy 13 in AML-M1. Here, we present two cases of elder male patients, which may constitute a distinct subtype.enAcute myeloid leukemia-M1recurrentsole abnormalitytrisomy 13AgedBone Marrow Cells --cytologyCells, CulturesChromosome Aberrations --geneticsChromosomes, Human, Pair 13 --geneticsHumansLymphocytes --bloodLymphocytes --cytologyIndia --epidemiologyIn Situ Hybridization, Fluorescence --methodsLeukemia, Myeloid, Acute --diagnosisLeukemia, Myeloid, Acute --geneticsMaleTrisomy --geneticsArticle