Athale, U ANair, RIyer, RNair, C NKadam, PAdvani, S H1991-05-012009-05-311991-05-012009-05-311991-05-01Athale UA, Nair R, Iyer R, Nair CN, Kadam P, Advani SH. Chronic myelomonocytic leukaemia (an analysis of fourteen consecutive cases). Journal of the Association of Physicians of India. 1991 May; 39(5): 390-3http://imsear.searo.who.int/handle/123456789/91787Fourteen consecutive cases of chronic myelomonocytic leukaemia aged 6 to 73 (mean 40.5) years were reviewed to define the natural history of the disease and the risk of acute transformation. The common presenting features included anaemia, fever, purpura, and bleeding tendencies. Abnormal karyotypes were seen in 4 of 6 patients subjected to cytogenetic analysis. Low dose cytosine arabinoside achieved complete remission in two and partial remission in one, of the four patients treated with this modality. The mean survival was 5.6 (range 2-12) months and two patients) evolved to acute myeloid leukaemia. The long term survival with the present form of therapy in chronic myelomonocytic leukaemia is poor.engAdolescentAdultAgedAntineoplastic Agents --therapeutic useBiopsy, NeedleBlood Cell CountBone Marrow --pathologyChildFemaleFetal Hemoglobin --analysisHumansIndiaLeukemia, Myelomonocytic, Chronic --diagnosisMaleMiddle AgedSurvival RateJournal Article