Nateghi, ZahraKhalilian, FatemehJanbakhsh, NoushinShirian, MohammadrezaShirian, Amirali2017-01-282017-01-282016Nateghi Zahra, Khalilian Fatemeh, Janbakhsh Noushin, Shirian Mohammadreza, Shirian Amirali. Porous Titanium Granules in Treatment of Intra-bony Defects: A Literature Review. British Journal of Medicine and Medical Research. 2016; 13(5): 1-10.2231-0614http://imsear.searo.who.int/handle/123456789/182541Background: This study aimed to do a review on the applications of porous titanium granules (PTG) in periodontal and non-periodontal treatments. Methods: An electronic search was carried out in Google Scholar and PubMed databases using the key words “guided tissue regeneration”, “intrabony defects”, “porous titanium granules” and “moderate to advanced chronic periodontitis”. English articles published from 2006 to 2014 were searched. Results: Porous titanium granules showed positive results in enhancing the outcome of treatment in medicine. Most of the relevant studies have been conducted using culture media or animal models. Conclusion: It can be stated that PTGs have many applications in periodontal procedures due to their space maintaining capability, long-term substantivity, not requiring a membrane and biocompatibility.enGuided tissue regenerationintrabony defectschronic periodontitisporous titanium granulesArticle