Naik, M SZade, P SJagtap, M K1979-07-012009-06-011979-07-012009-06-011979-07-01Naik MS, Zade PS, Jagtap MK. Histamine receptors in guinea-pig isolated urinary bladder. Indian Journal of Physiology and Pharmacology. 1979 Jul-Sep; 23(3): 234-6http://imsear.searo.who.int/handle/123456789/108334Spasmogenic action of histamine, 2-(2-aminoethyl) pyridine (H1 receptor agonist) and 4 methyl-histamine (H2 receptor agonist), have been studied in guinea pig isolated urinary bladder in the presence of mepyramine (H1 antagonist) and metiamide (H2 antagonist) to identify the presence of H1 and H2 receptors. The study suggested the presence of H1 as well as H2 receptors in this preparation.engAcetylcholine --pharmacologyAnimalsGuinea PigsHistamine --pharmacologyMaleMethylhistamines --pharmacologyMetiamide --pharmacologyPyridines --pharmacologyPyrilamine --pharmacologyReceptors, Histamine --drug effectsUrinary Bladder --drug effectsHistamine receptors in guinea-pig isolated urinary bladder.In Vitro