Rajesh, M GLatha, M S2001-10-092009-06-012001-10-092009-06-012001-10-09Rajesh MG, Latha MS. Hepatoprotection by Elephantopus scaber Linn. in CCl4-induced liver injury. Indian Journal of Physiology and Pharmacology. 2001 Oct; 45(4): 481-6http://imsear.searo.who.int/handle/123456789/108350The efficacy of the medicinal plant Elephantopus scaber Linn. (Asteraceae), to prevent carbon teterachloride (CCI4)-induced chronic liver dysfunction in the rats was examined by determining different biochemical markers in serum and tissues. In serum, liver function marker enzymes like aspartate aminotrasferase (AST), alanine aminotrasferase (ALT), alkaline phosphatase (ALP) and also protein were evaluated. The concentrations of total lipid, cholesterol and phospholipids were studied in serum and the different tissues. The concentration of serum triglycerides was also studied. The biochemical changes induced by CCI4 in different tissues particularly in the liver tissue improved following treatment with E. scaber Linn. The results suggest the hepatoprotective effect of this medicinal plant.engAlanine Transaminase --bloodAnimalsAspartate Aminotransferases --bloodBlood Proteins --analysisCarbon Tetrachloride --toxicityLiver --drug effectsMalePlants, MedicinalProtective Agents --pharmacologyRatsRats, Sprague-DawleyTriglycerides --bloodJournal Article