K., AshbinaRamakrishnan, K. G.Janardhanan, SujithNarayanan, SajithAziz, Feroz2024-11-302024-11-302024-01K. Ashbina, Ramakrishnan K. G., Janardhanan Sujith, Narayanan Sajith, Aziz Feroz. A Study of Serial Shearwave Sonoelastography (SWE) Using Supersonic Imaging in Early Renal Post - Transplant Period. Journal of Evolution of Medical and Dental Sciences. 2024 Jan; 13(1): 1-102278-48022278-4748https://imsear.searo.who.int/handle/123456789/238589BACKGROUND Ultrasound elastography is a novel technique in ultrasound that quantifies the tissue stiffness in organs and recently has emerged as a tool in complementing the evaluation of renal allograft function. The pathological processes underlying the graft dysfunction cause the changes in elasticity of the graft tissue. This change in elasticity is detected and imaged using elastography. US-based elastography is now a noninvasive complementary tool in addition to the existing laboratory and Doppler-based parameters in the evaluation of renal allograft dysfunction. METHODS The present prospective cohort study was conducted in the Department of Radiology, Malabar Institute of Medical sciences, Kerala, India from January 2019 to June 2020. RESULTS Renal allograft parenchymal stiffness by shearwave sonoelastography correlated positively with S. creatinine (p <0.001) and RI (p <0.001) and inversely correlated with eGFR (p<0.001). There was no correlation between the SWE values and BMI of the recipient. There was no correlation between the SWE values and age of the donor and between the SWE values and age of the patient. CONCLUSIONS The renal parenchymal stiffness by shearwave elastography showed positive correlation with serum creatinine and RI values and inverse correlation with eGFR which reflected the functional status of the renal allograft. The renal allografts with graft dysfunction were found to have higher SWE values than the stable renal allografts. The renal parenchymal stiffness can help to differentiate stable allografts and graft with allograft dysfunction, hence may be used as a reliable tool in addition to the existing laboratorical and Doppler based parameters in predicting allograft dysfunction. The cut-off value for differentiating stable renal allografts and renal allografts with dysfunction was found to be 14.32 kpa. There was no correlation between shear wave elastography values with the BMI of the recipient and age of the donor.SWERenal TransplantationSerum CreatinineRIeGFRBMI.Journal ArticleIndiaDepartment of Radiology, Malabar institute of medical sciences, Calicut, Kerala, IndiaDepartment of Radiology, Malabar institute of medical sciences, Calicut, Kerala, IndiaDepartment of Radiology, Malabar institute of medical sciences, Calicut, Kerala, IndiaDepartment of Nephrology, Malabar institute of medical sciences, Calicut, Kerala, IndiaDepartment of Nephrology, Malabar institute of medical sciences, Calicut, Kerala, India.