Gaur, BSaha, SIuliano, A DRai, SKKrishnan, AJain, SWhitaker, BWinchell, JLal, RBBroor, S2020-04-232020-04-232019-03Gaur B, Saha S, Iuliano A D, Rai SK, Krishnan A, Jain S, Whitaker B, Winchell J, Lal RB, Broor S. Use of TaqMan Array card for the detection of respiratory viral pathogens in children under 5 years old hospitalised with acute medical illness in Ballabgarh, Haryana, India. Indian Journal of Medical Microbiology. 2019 Mar; 37(1): 105-1080255-08571998-3646http://imsear.searo.who.int/handle/123456789/198845Historical specimens collected from hospitalized children were tested for the following 13 viruses: influenza A and B; respiratory syncytial virus (RSV); parainfluenza viruses 1� human metapneumovirus; rhinovirus; coronaviruses 229E, OC43, NL63 and HKU1 and Adenovirus using monoplex real-time reverse transcriptase polymerase chain reaction (rRT-PCR). They were retested using TaqMan Array Card (TAC), a micro-fluidic system, capable of simultaneous multi-pathogen testing, to evaluate its sensitivity and specificity against monoplex rRT-PCR. TAC showed high sensitivity (71%�0%) and specificity (98%�0%) for these viruses in comparison to monoplex rRT-PCR. Multi-specimen detection with high sensitivity and specificity makes TAC a potentially useful tool for both surveillance and outbreak investigations.Micro-fluidic cardsensitivityspecificityviral pathogen diagnosisJournal ArticleIndiaDepartment of Microbiology, All Institute of Medical Sciences, New Delhi, IndiaInfluenza Division, Centers for Disease Control and Prevention, U.S Embassy, New Delhi, IndiaInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, USACentre for Community Medicine, All Institute of Medical Sciences, New Delhi, IndiaDivision of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USADivision of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA