Mahata, Manoj KumarGhosh, SaikatGhosh, K. C.Bhattacharya, R.Mondal, G. P.2020-11-182020-11-182019-10Mahata Manoj Kumar, Ghosh Saikat, Ghosh K. C., Bhattacharya R., Mondal G. P.. Van der Knaap disease. International Journal of Research in Medical Sciences. 2019 Oct; 7(10): 3917-39192320-60712320-6012http://imsear.searo.who.int/handle/123456789/211681Van der Knaap disease is a rare form of leukodystrophy, phenotypically characterized by megalencephaly, early-onset ataxia, pyramidal features, cognitive impairment, with an autosomal recessive inheritence. MRI Brain shows T1 and FLAIR hypointense subcortical cysts in mostly temporal lobes and in fronto-parietal subcortical areas. Authors report a 20 yr. girl with typical features.LeukodystrophyMegalencephalySubcortical cystsVan der KnaapJournal ArticleIndiaDepartment of Neurosurgery, Hyogo College of Medicine, JapanConsultant Neurologist, Monorama Hospital, West Bengal, IndiaDepartment of Neuromedicine, Calcutta National Medical College, Kolkata, West Bengal, India