Meenakshi-Sundaram, SSridhar, RohiniJithendrian, J JDurai, R NArunkumar, M JSundar, Bharathi2005-07-302009-05-302005-07-302009-05-302005-07-30Meenakshi-Sundaram S, Sridhar R, Jithendrian JJ, Durai RN, Arunkumar MJ, Sundar B. Recurrent venous thrombosis with factor V Leiden mutation. Journal of the Association of Physicians of India. 2005 Jul; 53(): 642-4http://imsear.searo.who.int/handle/123456789/87148A patient who presented with recurrent venous thrombosis is reported. Following an episode of spontaneous deep vein thrombosis of the lower limb he was started on oral anticoagulant therapy, which he discontinued. He presented with cerebral venous thrombosis and improved partially with anticoagulant therapy. Evaluation for hypercoagulable states revealed factor V Leiden mutation by polymerized chain reaction method. Long-term anticoagulation has been planned. Evaluation for factor V Leiden mutation is always warranted in patients presenting with spontaneous thrombosis, especially if there is recurrent thrombosis.engAdultAnticoagulants --administration & dosageFactor V --geneticsHumansMaleMutationRecurrenceVenous Thrombosis --drug therapyCase Reports