Vyas, AnuragKumar, Chandra Shekhar2020-09-242020-09-242020-03Vyas Anurag, Kumar Chandra Shekhar. Prevalence of Subclinical Hypothyroidism of Patients with Acute Coronary Syndrome at a Tertiary Care Hospital. International Journal of Medical Research Professionals. 2020 Mar; 6(2): 108-1112454-63642454-6356http://imsear.searo.who.int/handle/123456789/203593Background: Cardiovascular diseases (CVDs) have nowbecome the leading cause of mortality in India. Acute coronarysyndrome (ACS) describes the range of myocardial ischemicstates that includes unstable angina, non-ST elevatedmyocardial infarction (MI), or ST-elevated MI. Hence; thepresent study was undertaken for assessing the prevalence ofsubclinical hypothyroidism of patients with acute coronarysyndrome.Materials & Methods: A total of 50 patients who wereadmitted due to acute coronary syndrome were enrolled in thepresent study. Blood samples were obtained and were sent tofor assessment of thyroid profile. Complete haematological andbiochemical profile of all the patients was also obtained. Forserum thyroid hormone profile was measured by Enzymelinked immunosorbent assay (ELISA) technique.Results: Subclinical hypothyroidism was found to be present in5 patients (10 percent of the patients). Non-significant resultswere obtained while correlating the presence of subclinicalhypothyroidism with age and gender-wise distribution ofpatients.Conclusion: Thyroid profile is altered significantly in patientswith acute coronary syndrome.Thyroid profile is altered significantly in patients with acute coronary syndromeJournal ArticleIndiaAssociate Professor, Department of General Medicine, Santosh Medical College and Hospital, Ghaziabad, Uttar Pradesh, IndiaAssistant Professor, Department of General Medicine, Rama Medical College Hospital & Research Centre, Hapur, Uttar Pradesh, India.